Dietary Fat-Carbohydrate Combinations: Their Effects on Lipid Metabolism in Estrogen-Treated Rats
نویسنده
چکیده
Female rats 4 weeks old were fed diets including beef tallow or safflower oil in combination with sucrose or rice starch. At 8 weeks of age, half the rats were orally administered 2 of estrogen (mestranol) in5 Ml of safflower oil and half were fed the vehicle only. After 10 to 14 days of estrogen treatment, rats were fasted and exsanguinated. Alterations were found in weight gain, liver weights, and levels of various lipids inplasma and liver.Most lipid levels were influenced by an interaction of mestranol with one of the dietary factors. No changes were observed in blood clotting activity as measured by prothrombin time and levels of plasma fibrinogen.
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